DNA Binding Motif

						

			
Accessions: MA0600.1 (JASPAR 2024)

			
Names: RFX2
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 19
Consensus: GTykCCaTGGCAACmrssv
Weblogo: 
PSSM: P0      A      C      G      T
01    373    141   1716    116      G
02     62    184    317   1783      T
03    192    736     64   1354      y
04    431    317    910    688      k
05     34   1936    121    255      C
06      1   2162      7    176      C
07   1567    432     41    306      a
08    164    222     94   1866      T
09    581      0   1765      0      G
10    193      5   2146      2      G
11    214   1932      0    200      C
12   2095      8    170     73      A
13   2312      0     28      6      A
14      0   2294      0     52      C
15    760    784    539    263      m
16    588    403   1178    177      r
17    406    831    733    376      s
18    585    630    761    370      s
19    620    668    678    380      v
Type: Heterodimer
Binding TFs: P48378 (RFX DNA-binding domain, RFX1 transcription activation region      )
P48378
Binding Sites: MA0600.1.1
MA0600.1.10
MA0600.1.11 / MA0600.1.13
MA0600.1.12 / MA0600.1.8
MA0600.1.14
MA0600.1.15
MA0600.1.16
MA0600.1.17
MA0600.1.18
MA0600.1.19
MA0600.1.2
MA0600.1.20
MA0600.1.3
MA0600.1.4
MA0600.1.5
MA0600.1.6
MA0600.1.7
MA0600.1.9
			
Publications: Emery P., Strubin M., Hofmann K., Bucher P., Mach B., Reith W. A consensus motif in the RFX DNA binding domain and binding domain mutants with altered specificity. Mol. Cell. Biol. 16:4486-4494 (1996). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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