DNA Binding Motif
| Accessions: | 5t7x_B (3D-footprint 20231221) |
| Names: | Epstein-Barr nuclear antigen 1 |
| Organisms: | Epstein-Barr virus (strain GD1) (HHV-4), Human herpesvirus 4 |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Description: | Crystal structure of HHV-4 EBNA1 DNA binding domain (patient-derived, nasopharyngeal carcinoma) bound to DNA |
| Length: | 7 |
| Consensus: | GGATAgc |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 0 0 96 0 G 02 0 0 96 0 G 03 96 0 0 0 A 04 0 0 0 96 T 05 96 0 0 0 A 06 16 13 54 13 g 07 13 54 13 16 c |
| Binding TFs: | 5t7x_B (Epstein Barr virus nuclear antigen-1, DNA-binding domain) |
| Binding Sites: | 5t7x_C 5t7x_D |
| Publications: | Dheekollu J, Malecka K, Wiedmer A, Delecluse HJ, Chiang AK, Altieri DC, Messick TE, Lieberman PM. Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency. Oncotarget 8:7248-7264 (2017). [Pubmed] |
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