DNA Binding Motif

Accessions: 5zko_ACGH (3D-footprint 20231221)
Names: Cyclic AMP-responsive element-binding protein 1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the CRTC2-CREB-CRE complex
Length: 12
Consensus: GCTGACGTCAGC
Weblogo:
PSSM: P0 A C G T
01 3 3 87 3 G
02 5 85 3 3 C
03 3 3 5 85 T
04 3 3 87 3 G
05 85 3 3 5 A
06 0 96 0 0 C
07 0 0 96 0 G
08 5 3 3 85 T
09 3 87 3 3 C
10 85 5 3 3 A
11 3 3 85 5 G
12 0 96 0 0 C
Binding TFs: 5zko_A / 5zko_C (bZIP transcription factor, Basic region leucine zipper)
Binding Sites: 5zko_B / 5zko_D
Publications: Song Y, Zhai L, Valencia Swain J, Chen Y, Wang P, Chen L, Liu Y, Xiang S. Structural Insights into the CRTC2-CREB Complex Assembly on CRE. J Mol Biol 430:1926-1939 (2018). [Pubmed]

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