DNA Binding Motif

Accessions: 1hrz_A (3D-footprint 20231221)
Names: HUMAN SRY
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: THE 3D STRUCTURE OF THE HUMAN SRY-DNA COMPLEX SOLVED BY MULTI-DIMENSIONAL HETERONUCLEAR-EDITED AND-FILTERED NMR
Length: 6
Consensus: ACAAac
Weblogo:
PSSM: P0 A C G T
01 96 0 0 0 A
02 0 96 0 0 C
03 96 0 0 0 A
04 96 0 0 0 A
05 54 16 13 13 a
06 16 54 13 13 c
Binding TFs: 1hrz_A (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Binding Sites: 1hrz_B
1hrz_C
Publications: Werner M. H., Huth J. R., Gronenborn A. M., Clore G. M. Molecular basis of human 46X,Y sex reversal revealed from the three-dimensional solution structure of the human SRY-DNA complex. Cell 81:705-714 (1995). [Pubmed]

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