DNA Binding Motif

Accessions: 1j46_A (3D-footprint 20231221)
Names: SEX-DETERMINING REGION Y PROTEIN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: 3D Solution NMR Structure of the Wild Type HMG-BOX Domain of the Human Male Sex Determining Factor Sry Complexed to DNA
Length: 7
Consensus: GTTTGTG
Weblogo:
PSSM: P0 A C G T
01 0 0 96 0 G
02 0 0 0 96 T
03 9 7 7 73 T
04 9 7 7 73 T
05 7 9 73 7 G
06 0 0 0 96 T
07 9 7 73 7 G
Binding TFs: 1j46_A (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Binding Sites: 1j46_B
1j46_C
Publications: Murphy E.C, Zhurkin V.B, Louis J.M, Cornilescu G, Clore G.M. Structural basis for SRY-dependent 46-X,Y sex reversal: modulation of DNA bending by a naturally occurring point mutation. Journal of molecular biology 312:481-99 (2001). [Pubmed]

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.