DNA Binding Motif

						

			
Accessions: NEUROD2_full (HumanTF 1.0), MA0668.1 (JASPAR 2024)

			
Names: NEUROD2
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 4, HT-SELEX
Length: 10
Consensus: rmCATATGky
Weblogo: 
PSSM: P0      A      C      G      T
01    604    119    769     95      r
02    527    875    240      0      m
03      0   1587     95      0      C
04   1587      0    308     52      A
05      0    156      0   1587      T
06   1587    120     38      4      A
07      0    328      0   1587      T
08      0      0   1587    112      G
09      0    373    705    548      k
10    209    592    101    685      y
Type: Heterodimer
Binding TFs: NEUROD2_full (Helix-loop-helix DNA-binding domain, Neuronal helix-loop-helix transcription factor )
Q15784 (Helix-loop-helix DNA-binding domain, Neuronal helix-loop-helix transcription factor )
Q15784
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Fong AP, Yao Z, Zhong JW, Cao Y, Ruzzo WL, Gentleman RC, Tapscott SJ. Genetic and epigenetic determinants of neurogenesis and myogenesis. Dev Cell 22:721-35 (2012). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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