DNA Binding Motif
| Accessions: | OTX1_DBD_2 (HumanTF 1.0), MA0711.1 (JASPAR 2024) |
| Names: | OTX1 |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF 1.0 1, JASPAR 2024 2 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | Site type: monomeric; SELEX cycle: 3, HT-SELEX |
| Length: | 8 |
| Consensus: | yTAATCcs |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 5118 6501 3186 8636 y 02 745 90 0 23441 T 03 23441 0 254 544 A 04 23441 0 0 0 A 05 243 0 3160 23441 T 06 647 23441 659 378 C 07 789 23441 8662 3363 c 08 1873 6182 10599 4787 s |
| Type: | Heterodimer |
| Binding TFs: | P32242 (Homeobox domain, Otx1 transcription factor) OTX1_DBD (Homeobox domain) P32242 |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] Noyes M.B, Christensen R.G, Wakabayashi A, Stormo G.D, Brodsky M.H, Wolfe S.A. Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 133:1277-89 (2008). [Pubmed] |
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