DNA Binding Motif

Accessions: 5egb_A (3D-footprint 20231221)
Names: Histone-lysine N-methyltransferase PRDM9
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Human PRDM9 allele-A ZnF Domain with Associated Recombination Hotspot DNA Sequence II
Length: 13
Consensus: tGGCTAGGGAGGC
Weblogo:
PSSM: P0 A C G T
01 16 16 16 48 t
02 0 0 96 0 G
03 0 0 96 0 G
04 0 96 0 0 C
05 0 16 0 80 T
06 96 0 0 0 A
07 0 0 96 0 G
08 0 0 96 0 G
09 0 0 96 0 G
10 80 16 0 0 A
11 0 0 96 0 G
12 0 0 96 0 G
13 0 96 0 0 C
Binding TFs: 5egb_A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Binding Sites: 5egb_C
5egb_D
Publications: Patel A, Horton JR, Wilson GG, Zhang X, Cheng X. Structural basis for human PRDM9 action at recombination hot spots. Genes Dev 30:257-65 (2016). [Pubmed]

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