DNA Binding Motif

						

			
Accessions: CUX1_NHLH1_1 (HumanTF2 1.0)

			
Names: CUX1_NHLH1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 23
Consensus: cGCAGCTGCkcmmamwATyGATy
Weblogo: 
PSSM: P0      A      C      G      T
01    168    362    131     49      c
02     73     39    549     48      G
03      4    709      0      9      C
04    709     10      6      5      A
05     23      6    709     14      G
06     77    709     32      0      C
07      0      3     13    709      T
08      0     25    709      6      G
09     54    580     27     48      C
10     12    158    287    252      k
11    173    291    119    125      c
12    191    378     21    119      m
13    200    375     78     56      m
14    349    135     83    142      a
15    196    222    127    164      m
16    303     25     99    281      w
17    709      0      1     38      A
18     34      5      3    709      T
19     14    709     11    634      y
20     86      0    709      5      G
21    709      0      1      5      A
22     43     20      0    709      T
23    124    250    120    215      y
Type: Heterodimer
Binding TFs: CUX1_TF1 (Homeobox domain, CUT domain, Homeobox KN domain)
NHLH1_TF2 (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.