DNA Binding Motif
| Accessions: | SigB_1 (DBTBS 1.0) |
| Names: | SigB_1 |
| Organisms: | Bacillus subtilis |
| Libraries: | DBTBS 1.0 1 1 Sierro N, Makita Y, de Hoon M, Nakai K. DBTBS: a database of transcriptional regulation in Bacillus subtilis containing upstream intergenic conservation information. Nucleic acids research 36:D93-6 (2008). [Pubmed] |
| Length: | 6 |
| Consensus: | GtTTaA |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 0 0.02 0.96 0.02 G 02 0.19 0 0.22 0.59 t 03 0 0 0.05 0.95 T 04 0.08 0 0 0.92 T 05 0.65 0.21 0 0.14 a 06 0.80 0 0.10 0.10 A |
| Binding TFs: | SigB (alpha/beta hydrolase fold, Alpha/beta hydrolase family, Alpha/beta hydrolase family) |
| Binding Sites: | aldY bmrU cdd_2 clpP_3 csbA_2 csbB_1 csbC csbD csbX ctc ctsR_3 dps_1 gsiB gspA gtaB_2 katE_1 katX_1 nadE_2 opuE_2 phoP_9 relA rsbV trxA_2 yacL ycnH ydaD ydaG ydaP ydaS ydaT ydbD ydbP ydfO ydhK yfhK yfkJ_2 yflA yhdF yhdN yjbC_1 yjgB ykgA ykzA yocK yotK yoxA_1 yoxC ypuB yqgZ yqhA yqhQ_1 yqxD_3 yqxL_2 yrvD ytkL ytxG_1 yvrE yvyD_1 ywjC ywmE ywtG yxkO yycD |
| Publications: | Huang X, Helmann J.D. Identification of target promoters for the Bacillus subtilis sigma X factor using a consensus-directed search. Journal of molecular biology 279:165-73 (1998). [Pubmed] Petersohn A, Bernhardt J, Gerth U, Höper D, Koburger T, Völker U, Hecker M. Identification of sigma(B)-dependent genes in Bacillus subtilis using a promoter consensus-directed search and oligonucleotide hybridization. Journal of bacteriology 181:5718-24 (1999). [Pubmed] Petersohn A, Antelmann H, Gerth U, Hecker M. Identification and transcriptional analysis of new members of the sigmaB regulon in Bacillus subtilis. Microbiology (Reading, England) 145 ( Pt 4):869-80 (1999). [Pubmed] Wang P.Z, Doi R.H. Overlapping promoters transcribed by bacillus subtilis sigma 55 and sigma 37 RNA polymerase holoenzymes during growth and stationary phases. The Journal of biological chemistry 259:8619-25 (1984). [Pubmed] Kiskin N.I, Krishtal O.A, Tsyndrenko AYa , Akaike N. Are sulfhydryl groups essential for function of the glutamate-operated receptor-ionophore complex?. Neuroscience letters 66:305-10 (1986). [Pubmed] Gerth U, Krüger E, Derré I, Msadek T, Hecker M. Stress induction of the Bacillus subtilis clpP gene encoding a homologue of the proteolytic component of the Clp protease and the involvement of ClpP and ClpX in stress tolerance. Molecular microbiology 28:787-802 (1998). [Pubmed] Völker U, Engelmann S, Maul B, Riethdorf S, Völker A, Schmid R, Mach H, Hecker M. Analysis of the induction of general stress proteins of Bacillus subtilis. Microbiology (Reading, England) 140 ( Pt 4):741-52 (1994). [Pubmed] Boylan S.A, Thomas M.D, Price C.W. Genetic method to identify regulons controlled by nonessential elements: isolation of a gene dependent on alternate transcription factor sigma B of Bacillus subtilis. Journal of bacteriology 173:7856-66 (1991). [Pubmed] Akbar S, Price C.W. Isolation and characterization of csbB, a gene controlled by Bacillus subtilis general stress transcription factor sigma B. Gene 177:123-8 (1996). [Pubmed] Akbar S, Lee S.Y, Boylan S.A, Price C.W. Two genes from Bacillus subtilis under the sole control of the general stress transcription factor sigmaB. Microbiology (Reading, England) 145 ( Pt 5):1069-78 (1999). [Pubmed] Gomez M, Cutting S.M. Identification of a new sigmaB-controlled gene, csbX, in Bacillus subtilis. Gene 188:29-33 (1997). [Pubmed] Ollington J.F, Haldenwang W.G, Huynh T.V, Losick R. Developmentally regulated transcription in a cloned segment of the Bacillus subtilis chromosome. Journal of bacteriology 147:432-42 (1981). [Pubmed] Moran C.P, Lang N, Losick R. Nucleotide sequence of a Bacillus subtilis promoter recognized by Bacillus subtilis RNA polymerase containing sigma 37. Nucleic acids research 9:5979-90 (1981). [Pubmed] Tatti K.M, Moran C.P. Promoter recognition by sigma-37 RNA polymerase from Bacillus subtilis. Journal of molecular biology 175:285-97 (1984). [Pubmed] Igo M.M, Losick R. Regulation of a promoter that is utilized by minor forms of RNA polymerase holoenzyme in Bacillus subtilis. Journal of molecular biology 191:615-24 (1986). [Pubmed] Boylan S.A, Redfield A.R, Brody M.S, Price C.W. Stress-induced activation of the sigma B transcription factor of Bacillus subtilis. Journal of bacteriology 175:7931-7 (1993). [Pubmed] Krüger E, Msadek T, Hecker M. Alternate promoters direct stress-induced transcription of the Bacillus subtilis clpC operon. Molecular microbiology 20:713-23 (1996). [Pubmed] Antelmann H, Engelmann S, Schmid R, Sorokin A, Lapidus A, Hecker M. Expression of a stress- and starvation-induced dps/pexB-homologous gene is controlled by the alternative sigma factor sigmaB in Bacillus subtilis. Journal of bacteriology 179:7251-6 (1997). [Pubmed] Antelmann H, Scharf C, Hecker M. Phosphate starvation-inducible proteins of Bacillus subtilis: proteomics and transcriptional analysis. Journal of bacteriology 182:4478-90 (2000). [Pubmed] Maul B, Völker U, Riethdorf S, Engelmann S, Hecker M. sigma B-dependent regulation of gsiB in response to multiple stimuli in Bacillus subtilis. Molecular & general genetics : MGG 248:114-20 (1995). [Pubmed] Mueller J.P, Bukusoglu G, Sonenshein A.L. Transcriptional regulation of Bacillus subtilis glucose starvation-inducible genes: control of gsiA by the ComP-ComA signal transduction system. Journal of bacteriology 174:4361-73 (1992). [Pubmed] Antelmann H, Bernhardt J, Schmid R, Hecker M. A gene at 333 degrees on the Bacillus subtilis chromosome encodes the newly identified sigma B-dependent general stress protein GspA. Journal of bacteriology 177:3540-5 (1995). [Pubmed] Varón D, Boylan S.A, Okamoto K, Price C.W. Bacillus subtilis gtaB encodes UDP-glucose pyrophosphorylase and is controlled by stationary-phase transcription factor sigma B. Journal of bacteriology 175:3964-71 (1993). [Pubmed] Engelmann S, Lindner C, Hecker M. Cloning, nucleotide sequence, and regulation of katE encoding a sigma B-dependent catalase in Bacillus subtilis. Journal of bacteriology 177:5598-605 (1995). [Pubmed] Petersohn A, Engelmann S, Setlow P, Hecker M. The katX gene of Bacillus subtilis is under dual control of sigmaB and sigmaF. Molecular & general genetics : MGG 262:173-9 (1999). [Pubmed] Antelmann H, Schmid R, Hecker M. The NAD synthetase NadE (OutB) of Bacillus subtilis is a sigma B-dependent general stress protein. FEMS microbiology letters 153:405-9 (1997). [Pubmed] von Blohn C, Kempf B, Kappes R.M, Bremer E. Osmostress response in Bacillus subtilis: characterization of a proline uptake system (OpuE) regulated by high osmolarity and the alternative transcription factor sigma B. Molecular microbiology 25:175-87 (1997). [Pubmed] Spiegelhalter F, Bremer E. Osmoregulation of the opuE proline transport gene from Bacillus subtilis: contributions of the sigma A- and sigma B-dependent stress-responsive promoters. Molecular microbiology 29:285-96 (1998). [Pubmed] Paul S, Birkey S, Liu W, Hulett F.M. Autoinduction of Bacillus subtilis phoPR operon transcription results from enhanced transcription from EsigmaA- and EsigmaE-responsive promoters by phosphorylated PhoP. Journal of bacteriology 186:4262-75 (2004). [Pubmed] Wendrich T.M, Marahiel M.A. Cloning and characterization of a relA/spoT homologue from Bacillus subtilis. Molecular microbiology 26:65-79 (1997). [Pubmed] Kalman S, Duncan M.L, Thomas S.M, Price C.W. Similar organization of the sigB and spoIIA operons encoding alternate sigma factors of Bacillus subtilis RNA polymerase. Journal of bacteriology 172:5575-85 (1990). [Pubmed] Scharf C, Riethdorf S, Ernst H, Engelmann S, Völker U, Hecker M. Thioredoxin is an essential protein induced by multiple stresses in Bacillus subtilis. Journal of bacteriology 180:1869-77 (1998). [Pubmed] Price C.W, Fawcett P, Cérémonie H, Su N, Murphy C.K, Youngman P. Genome-wide analysis of the general stress response in Bacillus subtilis. Molecular microbiology 41:757-74 (2001). [Pubmed] Völker U, Andersen K.K, Antelmann H, Devine K.M, Hecker M. One of two osmC homologs in Bacillus subtilis is part of the sigmaB-dependent general stress regulon. Journal of bacteriology 180:4212-8 (1998). [Pubmed] Liao C.T, Wen Y.D, Wang W.H, Chang B.Y. Identification and characterization of a stress-responsive promoter in the macromolecular synthesis operon of Bacillus subtilis. Molecular microbiology 33:377-88 (1999). [Pubmed] Varón D, Brody M.S, Price C.W. Bacillus subtilis operon under the dual control of the general stress transcription factor sigma B and the sporulation transcription factor sigma H. Molecular microbiology 20:339-50 (1996). [Pubmed] Drzewiecki K, Eymann C, Mittenhuber G, Hecker M. The yvyD gene of Bacillus subtilis is under dual control of sigmaB and sigmaH. Journal of bacteriology 180:6674-80 (1998). [Pubmed] Eymann C, Hecker M. Induction of sigma(B)-dependent general stress genes by amino acid starvation in a spo0H mutant of Bacillus subtilis. FEMS microbiology letters 199:221-7 (2001). [Pubmed] |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.