DNA Binding Motif

Accessions: KLF10_ChIP (humanC2H2ZF-ChIP Feb2015), KLF14_ChIP (humanC2H2ZF-ChIP Feb2015)
Names: KLF10, KLF14
Organisms: Homo sapiens
Libraries: humanC2H2ZF-ChIP Feb2015 1
1 Najafabadi HS, Mnaimneh S, Schmitges FW, Garton M, Lam KN, Yang A, Albu M, Weirauch MT, Radovani E, Kim PM, Greenblatt J, Frey BJ, Hughes TR. C2H2 zinc finger proteins greatly expand the human regulatory lexicon. Nat Biotechnol 33:555-62 (2015). [Pubmed]
Length: 9
Consensus: wGGGyGkGG
Weblogo:
PSSM: P0 A C G T
01 0.3386 0.0187 0.2357 0.4071 w
02 0.0203 0.0021 0.9763 0.0014 G
03 0.0032 0.0030 0.9908 0.0030 G
04 0.0032 0.0083 0.9848 0.0037 G
05 0.0637 0.4419 0.0025 0.4918 y
06 0.0051 0.0035 0.9836 0.0078 G
07 0.0097 0.0184 0.5017 0.4702 k
08 0.0609 0.0106 0.8997 0.0288 G
09 0.0284 0.0300 0.8748 0.0667 G
Type: Heterodimer
Binding TFs: KLF14 (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
KLF10 (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Publications: Najafabadi HS, Mnaimneh S, Schmitges FW, Garton M, Lam KN, Yang A, Albu M, Weirauch MT, Radovani E, Kim PM, Greenblatt J, Frey BJ, Hughes TR. C2H2 zinc finger proteins greatly expand the human regulatory lexicon. Nat Biotechnol 33:555-62 (2015). [Pubmed]

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