DNA Binding Motif

Accessions: 6amk_AB (3D-footprint 20231221)
Names: Putative DNA-binding protein
Organisms: strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745, Streptomyces venezuelae
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of Streptomyces venezuelae BldC-whiI opt complex
Length: 14
Consensus: TGTCCnnnnTGCCA
Weblogo:
PSSM: P0 A C G T
01 4 4 6 82 T
02 0 0 96 0 G
03 6 4 4 82 T
04 0 96 0 0 C
05 4 87 1 4 C
06 24 24 24 24 n
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 4 4 6 82 T
11 8 6 78 4 G
12 4 82 6 4 C
13 0 96 0 0 C
14 80 8 4 4 A
Type: Heterodimer
Binding TFs: 6amk_A (MerR family regulatory protein, Helix-turn-helix domain, MerR HTH family regulatory protein)
6amk_B (MerR family regulatory protein, Helix-turn-helix domain, MerR HTH family regulatory protein)
Binding Sites: 6amk_R
6amk_Z
Publications: Schumacher MA, den Hengst CD, Bush MJ, Le TBK, Tran NT, Chandra G, Zeng W, Travis B, Brennan RG, Buttner MJ. The MerR-like protein BldC binds DNA direct repeats as cooperative multimers to regulate Streptomyces development. Nat Commun 9:1139 (2018). [Pubmed]

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