DNA Binding Motif

Accessions: 5z2t_CD (3D-footprint 20231221)
Names: Double homeobox protein 4
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of DNA-bound DUX4-HD2
Length: 8
Consensus: TTAsaTTA
Weblogo:
PSSM: P0 A C G T
01 4 4 4 84 T
02 9 9 9 69 T
03 88 2 2 4 A
04 22 25 27 22 s
05 49 15 17 15 a
06 1 1 2 92 T
07 9 9 11 67 T
08 96 0 0 0 A
Type: Heterodimer
Binding TFs: 5z2t_C (Homeobox domain, Homeobox KN domain)
5z2t_D (Homeobox domain, Homeobox KN domain)
Binding Sites: 5z2t_E
5z2t_F
Publications: Dong X, Zhang W, Wu H, Huang J, Zhang M, Wang P, Zhang H, Chen Z, Chen SJ, Meng G. Structural basis of DUX4/IGH-driven transactivation. Leukemia : (2018). [Pubmed]

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