DNA Binding Motif

						

			
Accessions: 3clc_ABCD (3D-footprint 20231221)

			
Names: Regulatory protein
Organisms: Enterobacter sp. RFL1396
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of the Restriction-Modification Controller Protein C.Esp1396I Tetramer in Complex with its Natural 35 Base-Pair Operator
Length: 33
Consensus: TGTnGACnnnnGnCACACGGnCnnnnATTCACA
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0      0     96      T
02      0      0     96      0      G
03      3      2      2     89      T
04     24     24     24     24      n
05     11      2     81      2      G
06     90      2      2      2      A
07      0     96      0      0      C
08     24     24     24     24      n
09     24     24     24     24      n
10     24     24     24     24      n
11     24     24     24     24      n
12     11      0     79      6      G
13     24     24     24     24      n
14      0     93      0      3      C
15     91      2      3      0      A
16      2     89      2      3      C
17     87      3      4      2      A
18      0     96      0      0      C
19      0      0     96      0      G
20      2      3     89      2      G
21     24     24     24     24      n
22      0     96      0      0      C
23     24     24     24     24      n
24     24     24     24     24      n
25     24     24     24     24      n
26     24     24     24     24      n
27     70      6     12      8      A
28      0      0      4     92      T
29      0      0      0     96      T
30      4     79      7      6      C
31     90      2      2      2      A
32      0     96      0      0      C
33     96      0      0      0      A
Type: Heterodimer
Binding TFs: 3clc_A / 3clc_D (Helix-turn-helix, Helix-turn-helix domain)
3clc_B / 3clc_C (Helix-turn-helix, Helix-turn-helix domain)
Binding Sites: 3clc_E
3clc_F
			
Publications: McGeehan J.E, Streeter S.D, Thresh S.J, Ball N, Ravelli R.B, Kneale G.G. Structural analysis of the genetic switch that regulates the expression of restriction-modification genes. Nucleic acids research 36:4778-87 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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