DNA Binding Motif

Accessions: Cra (RegulonDB 7.5)
Names: Cra, Cra DNA-binding transcriptional dual regulator
Organisms: ECK12
Libraries: RegulonDB 7.5 1
1 Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muniz-Rascado L, Garcia-Sotelo JS, Weiss V, Solano-Lira H, Martinez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernandez S, Alquicira-Hernandez K, Lopez-Fuentes A, Porron-Sotelo L, Huerta AM, Bonavides-Martinez C, Balderas-Martinez YI, Pannier L, Olvera M, Labastida A, Jimenez-Jacinto V, Vega-Alvarado L, Del Moral-Chavez V, Hernandez-Alvarez A, Morett E, Collado-Vides J. RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more. Nucleic Acids Res. 2013 Jan 1;41(D1):D203-D213. [Pubmed]
Length: 18
Consensus: kwGCTGAAwCGwTTmAry
Weblogo:
PSSM: P0 A C G T
01 5 7 10 10 k
02 15 3 3 11 w
03 4 0 25 3 G
04 2 24 5 1 C
05 4 0 2 26 T
06 6 0 24 2 G
07 31 0 1 0 A
08 31 0 0 1 A
09 10 0 1 21 w
10 0 27 1 4 C
11 3 1 27 1 G
12 9 6 5 12 w
13 2 0 4 26 T
14 6 4 0 22 T
15 11 18 0 3 m
16 22 1 4 5 A
17 13 4 13 2 r
18 1 8 6 17 y
Binding TFs: ECK120004808 (Bacterial regulatory proteins, lacI family, Periplasmic binding proteins and sugar binding domain of LacI family, Periplasmic binding protein-like domain, Periplasmic binding protein domain)
Binding Sites: ECK120013116
ECK120013299
ECK120013384
ECK120013568
ECK120013645
ECK120013774
ECK120013776
ECK120013778
ECK120014083
ECK120014095
ECK120014161
ECK120015594
ECK120048912
ECK120048915
ECK120048991
ECK125134869
ECK125134872
ECK125134874
ECK125134876
ECK125134878
ECK125134880
ECK125134882
ECK125134884
ECK125134886
ECK125134888
ECK125134890
ECK125134892
ECK125134940
ECK125140726
ECK125140728
ECK125140730
ECK125140732
Publications: Mikulskis A., Aristarkhov A., Lin EC. Regulation of expression of the ethanol dehydrogenase gene (adhE) in Escherichia coli by catabolite repressor activator protein Cra. J Bacteriol. 179(22):7129-34 (1997). [Pubmed]

Kaga N., Umitsuki G., Clark DP., Nagai K., Wachi M. Extensive overproduction of the AdhE protein by rng mutations depends on mutations in the cra gene or in the Cra-box of the adhE promoter. Biochem Biophys Res Commun. 295(1):92-7 (2002). [Pubmed]

Saier MH., Ramseier TM. The catabolite repressor/activator (Cra) protein of enteric bacteria. J Bacteriol. 178(12):3411-7 (1996). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.