DNA Binding Motif

Accessions: 5e01_AB (3D-footprint 2022-04-03)
Names: Uncharacterized HTH-type transcriptional regulator HI_0186
Organisms: Haemophilus influenzae, strain ATCC 51907 / DSM 11121 / KW20 / Rd
Libraries: 3D-footprint 2022-04-03 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of HiNmlR, a MerR family regulator lacking the sensor domain, bound to palyndromic promoter DNA
Length: 12
Consensus: AGAGnnnnCTCT
Weblogo:
PSSM: P0 A C G T
01 82 6 4 4 A
02 5 0 87 4 G
03 82 4 6 4 A
04 4 4 82 6 G
05 24 24 24 24 n
06 24 24 24 24 n
07 24 24 24 24 n
08 24 24 24 24 n
09 4 82 6 4 C
10 4 4 6 82 T
11 4 82 4 6 C
12 1 4 0 91 T
Type: Heterodimer
Binding TFs: 5e01_A (MerR family regulatory protein, MerR, DNA binding, MerR HTH family regulatory protein)
5e01_B (MerR family regulatory protein, MerR, DNA binding, MerR HTH family regulatory protein)
Binding Sites: 5e01_C / 5e01_D
Publications: Couñago RM, Chen NH, Chang CW, Djoko KY, McEwan AG, Kobe B. Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region 44:6981-93 (Nucleic). [Pubmed]

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