DNA Binding Motif

Accessions: 5kl7_A (3D-footprint 2022-04-03)
Names: Wilms tumor protein
Organisms: Homo sapiens
Libraries: 3D-footprint 2022-04-03 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Wilms Tumor Protein (WT1) ZnF2-4Q369R in complex with carboxylated DNA
Length: 9
Consensus: AGCCCACGC
Weblogo:
PSSM: P0 A C G T
01 67 9 11 9 A
02 0 0 96 0 G
03 0 96 0 0 C
04 0 96 0 0 C
05 0 96 0 0 C
06 96 0 0 0 A
07 9 67 9 11 C
08 0 0 96 0 G
09 9 69 9 9 C
Binding TFs: 5kl7_A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Binding Sites: 5kl7_B
5kl7_C
Publications: Hashimoto H, Zhang X, Zheng Y, Wilson GG, Cheng X. Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications. Nucleic Acids Res 44:10165-10176 (2016). [Pubmed]

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