DNA Binding Motif

Accessions: 6y93_AB (3D-footprint 20231221)
Names: Nucleoid occlusion protein
Organisms: Bacillus subtilis, strain 168
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the DNA-binding domain of the Nucleoid Occlusion Factor (Noc) complexed to the Noc-binding site (NBS)
Length: 16
Consensus: TATTTCCngGGAAATA
Weblogo:
PSSM: P0 A C G T
01 0 0 0 96 T
02 96 0 0 0 A
03 0 0 0 96 T
04 0 0 0 96 T
05 0 0 0 96 T
06 0 96 0 0 C
07 0 96 0 0 C
08 24 24 24 24 n
09 19 20 38 19 g
10 0 0 96 0 G
11 0 0 96 0 G
12 96 0 0 0 A
13 96 0 0 0 A
14 96 0 0 0 A
15 0 0 0 96 T
16 76 0 1 19 A
Binding TFs: 6y93_A (Helix-turn-helix, KorB domain)
Binding Sites: 6y93_C / 6y93_D
Publications: Jalal ASB, Tran NT, Stevenson CE, Chan EW, Lo R, Tan X, Noy A, Lawson DM, Le TBK. Diversification of DNA-Binding Specificity by Permissive and Specificity-Switching Mutations in the ParB/Noc Protein Family. Cell Rep 32:107928 (2020). [Pubmed]

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