DNA Binding Motif

						

			
Accessions: ATF7_DBD (HumanTF 1.0), MA0834.1 (JASPAR 2024)

			
Names: ATF7
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 4, HT-SELEX
Length: 14
Consensus: crATGACGTCAYmv
Weblogo: 
PSSM: P0      A      C      G      T
01   3922   6606   4161   4641      c
02   5130   2440   7299   4461      r
03  19329    368   3772     41      A
04     11      4     43  19329      T
05     26      7  19329   1759      G
06  19329      8     58     12      A
07     20  19329     33     68      C
08     79      9  19329      4      G
09     25     16     77  19329      T
10   2698  19329     51     22      C
11  19329      2     49     11      A
12     82   7305    440  19329      Y
13   5628   8116   2129   3456      m
14   5680   4920   5892   2839      v
Type: Heterodimer
Binding TFs: P17544 (bZIP transcription factor, Basic region leucine zipper)
P17544 (bZIP transcription factor, Basic region leucine zipper)
ATF7_DBD (bZIP transcription factor, Basic region leucine zipper)
P17544
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Hai T., Liu F., Coukos W. J., Green M. R. Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers. Genes Dev. 3:2083-2090 (1989). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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