DNA Binding Motif

Accessions: 1efa_B (3D-footprint 20231221)
Names: LAC REPRESSOR
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CRYSTAL STRUCTURE OF THE LAC REPRESSOR DIMER BOUND TO OPERATOR AND THE ANTI-INDUCER ONPF
Length: 9
Consensus: CGCTCACAA
Weblogo:
PSSM: P0 A C G T
01 9 73 7 7 C
02 0 0 96 0 G
03 7 73 7 9 C
04 7 7 9 73 T
05 0 96 0 0 C
06 96 0 0 0 A
07 0 96 0 0 C
08 96 0 0 0 A
09 73 7 9 7 A
Binding TFs: 1efa_B (Bacterial regulatory proteins, lacI family, Periplasmic binding proteins and sugar binding domain of LacI family, Periplasmic binding protein-like domain, Periplasmic binding protein domain)
Binding Sites: 1efa_D
1efa_E
Publications: Bell C.E, Lewis M. A closer view of the conformation of the Lac repressor bound to operator. Nature structural biology 7:209-14 (2000). [Pubmed]

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