DNA Binding Motif

Accessions: 1srs_AB (3D-footprint 20210203)
Names: PROTEIN (SERUM RESPONSE FACTOR (SRF))
Organisms: Homo sapiens
Libraries: 3D-footprint 20210203 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: SERUM RESPONSE FACTOR (SRF) CORE COMPLEXED WITH SPECIFIC SRE DNA
Length: 10
Consensus: CCTAatTAGk
Weblogo:
PSSM: P0 A C G T
01 0 96 0 0 C
02 0 96 0 0 C
03 4 1 1 90 T
04 90 1 1 4 A
05 50 18 19 9 a
06 20 13 13 50 t
07 0 0 0 96 T
08 91 1 3 1 A
09 1 1 92 2 G
10 1 4 64 27 k
Type: Heterodimer
Binding TFs: 1srs_A (SRF-type transcription factor (DNA-binding and dimerisation domain))
1srs_B (SRF-type transcription factor (DNA-binding and dimerisation domain))
Binding Sites: 1srs_C
1srs_W
Publications: Pellegrini L., Tan S., Richmond T. J. Structure of serum response factor core bound to DNA. Nature 376:490-498 (1995). [Pubmed]

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