DNA Binding Motif

Accessions: 1osl_B (3D-footprint 20231221)
Names: Lactose operon repressor
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Solution structure of a dimeric lactose DNA-binding domain complexed to a nonspecific DNA sequence
Length: 8
Consensus: atwagata
Weblogo:
PSSM: P0 A C G T
01 52 16 14 14 a
02 19 16 16 45 t
03 27 22 22 25 w
04 63 10 13 10 a
05 13 14 56 13 g
06 38 20 19 19 a
07 21 23 21 31 t
08 38 19 19 20 a
Binding TFs: 1osl_B (Bacterial regulatory proteins, lacI family)
Binding Sites: 1osl_C / 1osl_D
Publications: Kalodimos C.G, Biris N, Bonvin A.M, Levandoski M.M, Guennuegues M, Boelens R, Kaptein R. Structure and flexibility adaptation in nonspecific and specific protein-DNA complexes. Science (New York, N.Y.) 305:386-9 (2004). [Pubmed]

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