DNA Binding Motif

						

			
Accessions: TFAP2C_DBD_1 (HumanTF 1.0), MA0524.2 (JASPAR 2024)

			
Names: TFAP2C
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 3, HT-SELEX
Length: 12
Consensus: tGCCyyrrGGCa
Weblogo: 
PSSM: P0      A      C      G      T
01   1289   1427    308   2810      t
02    878   1693   5834    139      G
03     70   5834    621     51      C
04     24   5834      9    121      C
05     37   3594    384   1820      y
06    516   2124   1327   1867      y
07   2405   1450   1702    277      r
08   2216    341   3261     17      r
09    163     12   5834     16      G
10    111    742   5834     37      G
11    254   5834   1172    599      C
12   3485    389   1035    925      a
Type: Heterodimer
Binding TFs: Q92754 (Transcription factor AP-2)
TFAP2C_DBD (Transcription factor AP-2)
Q92754
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Eckert D, Buhl S, Weber S, Jäger R, Schorle H. The AP-2 family of transcription factors. Genome Biol : (2005;6(13):246.). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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