DNA Binding Motif

						

			
Accessions: RXRG_DBD_1 (HumanTF 1.0), MA0856.1 (JASPAR 2024)

			
Names: RXRG
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 3, HT-SELEX
Length: 14
Consensus: grGGTCAAAGGTCA
Weblogo: 
PSSM: P0      A      C      G      T
01   7824   3800  21426   1886      g
02  14207     63  20865     20      r
03     49      4  23554     77      G
04    102      9  22312   3946      G
05      5     35    126  39123      T
06     28  56980    734   3942      C
07  37922      0     76      4      A
08  34468     14    970    574      A
09  33003      0   1634      5      A
10      9      1  29532     20      G
11     12      1  27903   3913      G
12      2     17    134  37558      T
13     78  49963    935   2999      C
14  36677     43   2323     27      A
Type: Heterodimer
Binding TFs: P48443 (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains), Nuclear/hormone receptor activator site AF-1)
RXRG_DBD (Zinc finger, C4 type (two domains))
P48443
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Bastien J, Rochette-Egly C. Nuclear retinoid receptors and the transcription of retinoid-target genes. Gene : (2004). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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