DNA Binding Motif

						

			
Accessions: FOXB1_DBD_3 (HumanTF 1.0), MA0845.1 (JASPAR 2024)

			
Names: FOXB1
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 3, HT-SELEX
Length: 11
Consensus: wAwGTMAAyAt
Weblogo: 
PSSM: P0      A      C      G      T
01   2393    272    190   4448      w
02   5343    263   1498    561      A
03   1983    218    409   4858      w
04   1159     54   6841    124      G
05    180    240    113   6841      T
06   4891   1950     75     73      M
07   6841    213      0    381      A
08   6841     47     47    216      A
09     28   2252    104   4589      y
10   6841      0    157    147      A
11   1704    573    556   4008      t
Type: Heterodimer
Binding TFs: FOXB1_DBD (Fork head domain)
Q99853 (Fork head domain)
Q99853
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Kaufmann E., Mueller D., Knoechel W. DNA recognition site analysis of Xenopus winged helix proteins. J. Mol. Biol. 248:239-254 (1995). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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