DNA Binding Motif

Accessions: 1ynw_AB (3D-footprint 2022-04-03)
Names: Vitamin D3 Receptor
Organisms: Homo sapiens
Libraries: 3D-footprint 2022-04-03 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of Vitamin D Receptor and 9-cis Retinoic Acid Receptor DNA-Binding Domains Bound to a DR3 Response Element
Length: 14
Consensus: TGACCnnnnTGnCC
Weblogo:
PSSM: P0 A C G T
01 6 8 6 76 T
02 0 0 96 0 G
03 70 12 0 14 A
04 0 96 0 0 C
05 19 71 0 6 C
06 24 24 24 24 n
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 6 6 14 70 T
11 0 0 96 0 G
12 24 24 24 24 n
13 0 96 0 0 C
14 0 96 0 0 C
Type: Heterodimer
Binding TFs: 1ynw_A (Zinc finger, C4 type (two domains))
1ynw_B (Zinc finger, C4 type (two domains))
Binding Sites: 1ynw_C
1ynw_D
Publications: Shaffer P.L, Gewirth D.T. Structural analysis of RXR-VDR interactions on DR3 DNA. The Journal of steroid biochemistry and molecular biology 89-90:215-9 (2004). [Pubmed]

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