DNA Binding Motif

Accessions: 6jni_GH (3D-footprint 20231221)
Names: CadR
Organisms: Pseudomonas putida
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the transcriptional regulator CadR from P. putida in complex with Zinc(II) and DNA
Length: 21
Consensus: ACnnTATAGTnGCTACAnnGT
Weblogo:
PSSM: P0 A C G T
01 72 10 4 10 A
02 2 89 2 3 C
03 24 24 24 24 n
04 24 24 24 24 n
05 2 2 2 90 T
06 74 8 10 4 A
07 0 0 0 96 T
08 96 0 0 0 A
09 0 0 96 0 G
10 2 2 2 90 T
11 24 24 24 24 n
12 2 2 89 3 G
13 0 96 0 0 C
14 2 3 2 89 T
15 96 0 0 0 A
16 2 89 3 2 C
17 91 2 0 3 A
18 24 24 24 24 n
19 24 24 24 24 n
20 3 2 89 2 G
21 10 4 2 80 T
Type: Heterodimer
Binding TFs: 6jni_G (MerR family regulatory protein, MerR, DNA binding, MerR HTH family regulatory protein)
6jni_H (MerR family regulatory protein, MerR, DNA binding, MerR HTH family regulatory protein)
Binding Sites: 6jni_O
6jni_P
Publications: Liu X, Hu Q, Yang J, Huang S, Wei T, Chen W, He Y, Wang D, Liu Z, Wang K, Gan J, Chen H. Selective cadmium regulation mediated by a cooperative binding mechanism in CadR. Proc Natl Acad Sci U S A 116:20398-20403 (2019). [Pubmed]

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