DNA Binding Motif

						

			
Accessions: ZNF143_DBD (HumanTF 1.0), MA0088.2 (JASPAR 2024)

			
Names: ZNF143
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 4, HT-SELEX
Length: 16
Consensus: ywCCCAyAATGCAyyG
Weblogo: 
PSSM: P0      A      C      G      T
01     87    509    153   1285      y
02    949      0     13    652      w
03     21   1590      1      1      C
04      2   1609      0      0      C
05      0   1609      0      0      C
06   1609      0      4      3      A
07      0    917     61    686      y
08   1295    143    310      0      A
09   1572      0     67      1      A
10      6      0      1   1609      T
11     59     36   1553      9      G
12      0   1609      0      0      C
13   1503    153      3     27      A
14    345   1067     15   1080      y
15    102   1138     13   1199      y
16    382     21   1518    120      G
Type: Heterodimer
Binding TFs: ZNF143_DBD (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
P52747 (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
P52747
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Schaub M., Myslinski E., Schuster C., Krol A., Carbon P. Staf, a promiscuous activator for enhanced transcription by RNA polymerases II and IIII. EMBO J. 16:173-181 (1997). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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