DNA Binding Motif

						

			
Accessions: 1r0n_AB (3D-footprint 20231221)

			
Names: Retinoic acid receptor RXR-alpha
Organisms: Homo sapiens, Drosophila melanogaster
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of Heterodimeric Ecdsyone receptor DNA binding complex
Length: 11
Consensus: GGnCAnTGaCC
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0     96      0      G
02      0      0     96      0      G
03     24     24     24     24      n
04      0     96      0      0      C
05     72     12     12      0      A
06     24     24     24     24      n
07     12      0     12     72      T
08      0      0     96      0      G
09     60     12     12     12      a
10      0     96      0      0      C
11      0     96      0      0      C
Type: Heterodimer
Binding TFs: 1r0n_A (Zinc finger, C4 type (two domains))
1r0n_B (Zinc finger, C4 type (two domains))
Binding Sites: 1r0n_C
1r0n_D
			
Publications: Devarakonda S, Harp J.M, Kim Y, Ozyhar A, Rastinejad F. Structure of the heterodimeric ecdysone receptor DNA-binding complex. The EMBO journal 22:5827-40 (2003). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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