DNA Binding Motif

Accessions: 3q5f_AB (3D-footprint 20231221)
Names: Transcriptional regulator slyA
Organisms: Salmonella enterica subsp. enterica serovar Typhimurium, strain LT2 / SGSC1412 / ATCC 700720
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the Salmonella transcriptional regulator SlyA in complex with DNA
Length: 20
Consensus: TAnntTAGCAAGCTAAnnAT
Weblogo:
PSSM: P0 A C G T
01 2 2 3 89 T
02 71 10 13 2 A
03 24 24 24 24 n
04 24 24 24 24 n
05 10 8 13 65 t
06 3 2 2 89 T
07 96 0 0 0 A
08 3 13 78 2 G
09 0 96 0 0 C
10 96 0 0 0 A
11 93 2 0 1 A
12 0 0 96 0 G
13 2 90 2 2 C
14 0 0 0 96 T
15 96 0 0 0 A
16 90 2 2 2 A
17 24 24 24 24 n
18 24 24 24 24 n
19 89 2 3 2 A
20 3 2 2 89 T
Type: Heterodimer
Binding TFs: 3q5f_A (MarR family, MarR family, Winged helix DNA-binding domain)
3q5f_B (MarR family, MarR family, Winged helix DNA-binding domain)
Binding Sites: 3q5f_C
3q5f_D
Publications: Dolan K.T, Duguid E.M, He C. Crystal structures of SlyA protein, a master virulence regulator of Salmonella, in free and DNA-bound states. The Journal of biological chemistry 286:22178-85 (2011). [Pubmed]

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