DNA Binding Motif

Accessions: Ada (RegulonDB 7.5)
Names: Ada, Ada DNA-binding transcriptional dual regulator
Organisms: ECK12
Libraries: RegulonDB 7.5 1
1 Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muniz-Rascado L, Garcia-Sotelo JS, Weiss V, Solano-Lira H, Martinez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernandez S, Alquicira-Hernandez K, Lopez-Fuentes A, Porron-Sotelo L, Huerta AM, Bonavides-Martinez C, Balderas-Martinez YI, Pannier L, Olvera M, Labastida A, Jimenez-Jacinto V, Vega-Alvarado L, Del Moral-Chavez V, Hernandez-Alvarez A, Morett E, Collado-Vides J. RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more. Nucleic Acids Res. 2013 Jan 1;41(D1):D203-D213. [Pubmed]
Length: 13
Consensus: AMkbWWWdmSCAR
Weblogo:
PSSM: P0 A C G T
01 4 0 0 0 A
02 3 1 0 0 M
03 0 0 2 2 k
04 0 2 1 1 b
05 3 0 0 1 W
06 3 0 0 1 W
07 3 0 0 1 W
08 1 0 2 1 d
09 2 2 0 0 m
10 0 1 3 0 S
11 0 4 0 0 C
12 4 0 0 0 A
13 3 0 1 0 R
Binding TFs: ECK120004502 (Bacterial regulatory helix-turn-helix proteins, AraC family, 6-O-methylguanine DNA methyltransferase, DNA binding domain, Metal binding domain of Ada, 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain, Helix-turn-helix domain)
Binding Sites: ECK120012597
ECK120012905
ECK120012982
ECK125110266
Publications: Landini P., Busby SJ. The Escherichia coli Ada protein can interact with two distinct determinants in the sigma70 subunit of RNA polymerase according to promoter architecture: identification of the target of Ada activation at the alkA promoter. J Bacteriol. 181(5):1524-9 (1999). [Pubmed]

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