DNA Binding Motif

						

			
Accessions: NFE2_DBD (HumanTF 1.0), MA0841.1 (JASPAR 2024)

			
Names: NFE2
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 4, HT-SELEX
Length: 11
Consensus: vATGACTCATs
Weblogo: 
PSSM: P0      A      C      G      T
01   5589   7208   5303    731      v
02  18831      9   1306      5      A
03      2      8      0  18831      T
04      0      0  18831      2      G
05  18831     11      0      4      A
06     37  14360   4472     17      C
07      0     20      3  18831      T
08      1  18831      0      3      C
09  18831     13      8      5      A
10      0   2689     10  18831      T
11    487   9860   5067   3417      s
Type: Heterodimer
Binding TFs: Q16621 (bZIP transcription factor, bZIP Maf transcription factor)
NFE2_DBD (bZIP transcription factor, bZIP Maf transcription factor, Basic region leucine zipper)
Q16621
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Daftari P, Gavva NR, Shen CK. Distinction between AP1 and NF-E2 factor-binding at specific chromatin regions in mammalian cells. Oncogene 18:5482-6 (1999). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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