DNA Binding Motif

Accessions: 4eot_AB (3D-footprint 20231221)
Names: Transcription factor MafA
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the MafA homodimer bound to the consensus MARE
Length: 13
Consensus: tGCnnACTnnGCa
Weblogo:
PSSM: P0 A C G T
01 13 16 13 54 t
02 0 0 96 0 G
03 0 96 0 0 C
04 24 24 24 24 n
05 24 24 24 24 n
06 96 0 0 0 A
07 0 96 0 0 C
08 0 0 0 96 T
09 24 24 24 24 n
10 24 24 24 24 n
11 0 0 96 0 G
12 0 96 0 0 C
13 54 16 13 13 a
Type: Heterodimer
Binding TFs: 4eot_A (bZIP Maf transcription factor)
4eot_B (bZIP Maf transcription factor)
Binding Sites: 4eot_C
4eot_D
Publications: Lu X, Guanga G.P, Wan C, Rose R.B. A Novel DNA Binding Mechanism for maf Basic Region-Leucine Zipper Factors Inferred from a MafA-DNA Complex Structure and Binding Specificities. Biochemistry : (2012). [Pubmed]

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