DNA Binding Motif

Accessions: 7gat_A (3D-footprint 20231221)
Names: NITROGEN REGULATORY PROTEIN AREA
Organisms: Emericella nidulans, Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: SOLUTION NMR STRUCTURE OF THE L22V MUTANT DNA BINDING DOMAIN OF AREA COMPLEXED TO A 13 BP DNA CONTAINING A TGATA SITE, 34 STRUCTURES
Length: 4
Consensus: TGat
Weblogo:
PSSM: P0 A C G T
01 0 0 0 96 T
02 0 0 96 0 G
03 54 13 16 13 a
04 13 13 16 54 t
Binding TFs: 7gat_A (GATA zinc finger)
Binding Sites: 7gat_B
7gat_C
Publications: Starich M.R, Wikström M, Schumacher S, Arst H.N, Gronenborn A.M, Clore G.M. The solution structure of the Leu22-->Val mutant AREA DNA binding domain complexed with a TGATAG core element defines a role for hydrophobic packing in the determination of specificity. Journal of molecular biology 277:621-34 (1998). [Pubmed]

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