DNA Binding Motif

Accessions: 1am9_AB (3D-footprint 20210203)
Names: PROTEIN (STEROL REGULATORY ELEMENT BINDING PROTEIN 1A)
Organisms: Homo sapiens
Libraries: 3D-footprint 20210203 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: HUMAN SREBP-1A BOUND TO LDL RECEPTOR PROMOTER
Length: 10
Consensus: gTCaCcCCaC
Weblogo:
PSSM: P0 A C G T
01 21 14 45 16 g
02 4 4 4 84 T
03 0 96 0 0 C
04 61 12 12 11 a
05 3 86 3 4 C
06 8 64 7 17 c
07 5 87 2 2 C
08 2 87 2 5 C
09 61 12 13 10 a
10 4 83 5 4 C
Type: Heterodimer
Binding TFs: 1am9_A (Helix-loop-helix DNA-binding domain)
1am9_B (Helix-loop-helix DNA-binding domain)
Binding Sites: 1am9_G
1am9_F
Publications: Párraga A, Bellsolell L, Ferré-D'Amaré A.R, Burley S.K. Co-crystal structure of sterol regulatory element binding protein 1a at 2.3 A resolution. Structure (London, England : 1993) 6:661-72 (1998). [Pubmed]

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