DNA Binding Motif

Accessions: 1am9_AB (3D-footprint 20231221)
Names: PROTEIN (STEROL REGULATORY ELEMENT BINDING PROTEIN 1A)
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: HUMAN SREBP-1A BOUND TO LDL RECEPTOR PROMOTER
Length: 10
Consensus: gTCaCcCCaC
Weblogo:
PSSM: P0 A C G T
01 21 14 45 16 g
02 4 4 4 84 T
03 0 96 0 0 C
04 61 12 12 11 a
05 3 86 3 4 C
06 8 64 7 17 c
07 5 87 2 2 C
08 2 87 2 5 C
09 61 12 13 10 a
10 4 83 5 4 C
Type: Heterodimer
Binding TFs: 1am9_A (Helix-loop-helix DNA-binding domain)
1am9_B (Helix-loop-helix DNA-binding domain)
Binding Sites: 1am9_G
1am9_F
Publications: Párraga A, Bellsolell L, Ferré-D'Amaré A.R, Burley S.K. Co-crystal structure of sterol regulatory element binding protein 1a at 2.3 A resolution. Structure (London, England : 1993) 6:661-72 (1998). [Pubmed]

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.