DNA Binding Motif

						

			
Accessions: OLIG2_full (HumanTF 1.0), MA0678.1 (JASPAR 2024)

			
Names: OLIG2
Organisms: Homo sapiens, Mus musculus
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 4, HT-SELEX
Length: 10
Consensus: AmCATATGky
Weblogo: 
PSSM: P0      A      C      G      T
01   1609     90    283    108      A
02    680    929    142     16      m
03     74   1609      4      0      C
04   1609      2     53     22      A
05      0      0      0   1609      T
06   1609     22     18      4      A
07     21    159      0   1609      T
08     10      3   1609    117      G
09      4    396    866    744      k
10    146    689     57   1609      y
Type: Heterodimer
Binding TFs: OLIG2_full (Helix-loop-helix DNA-binding domain)
Q13516 (Helix-loop-helix DNA-binding domain)
Q13516
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Küspert M, Hammer A, Bösl MR, Wegner M. Olig2 regulates Sox10 expression in oligodendrocyte precursors through an evolutionary conserved distal enhancer. Nucleic Acids Res 39:1280-93 (2011). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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