DNA Binding Motif

Accessions: 3mu6_AB (3D-footprint 2022-04-03)
Names: Myocyte-specific enhancer factor 2A
Organisms: Homo sapiens
Libraries: 3D-footprint 2022-04-03 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Inhibiting the Binding of Class IIa Histone Deacetylases to Myocyte Enhancer Factor-2 by Small Molecules
Length: 10
Consensus: CTAnnnnTAG
Weblogo:
PSSM: P0 A C G T
01 9 87 0 0 C
02 0 9 0 87 T
03 67 11 9 9 A
04 24 24 24 24 n
05 24 24 24 24 n
06 24 24 24 24 n
07 24 24 24 24 n
08 9 9 9 69 T
09 87 0 9 0 A
10 0 0 96 0 G
Binding TFs: 3mu6_A / 3mu6_B (SRF-type transcription factor (DNA-binding and dimerisation domain))
Binding Sites: 3mu6_E
3mu6_F
Publications: Jayathilaka N, Han A, Gaffney K.J, Dey R, Jarusiewicz J.A, Noridomi K, Philips M.A, Lei X, He J, Ye J, Gao T, Petasis N.A, Chen L. Inhibition of the function of class IIa HDACs by blocking their interaction with MEF2. Nucleic acids research 40:5378-88 (2012). [Pubmed]

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