DNA Binding Motif
| Accessions: | PHOX2A_DBD (HumanTF 1.0), MA0713.1 (JASPAR 2024) |
| Names: | PHOX2A |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF 1.0 1, JASPAR 2024 2 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | Site type: dimeric; SELEX cycle: 3, HT-SELEX |
| Length: | 11 |
| Consensus: | TAAtyyAATTA |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 2164 1240 497 11434 T 02 11434 225 1539 1001 A 03 11434 0 34 5 A 04 1362 4424 629 11434 t 05 639 5304 2300 6130 y 06 1262 4580 806 6855 y 07 11434 717 1896 437 A 08 11434 199 309 132 A 09 0 10 2 11434 T 10 1135 778 81 11434 T 11 11434 229 816 1657 A |
| Type: | Heterodimer |
| Binding TFs: | PHOX2A_DBD (Homeobox domain) O14813 (Homeobox domain) O14813 |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] Noyes M.B, Christensen R.G, Wakabayashi A, Stormo G.D, Brodsky M.H, Wolfe S.A. Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 133:1277-89 (2008). [Pubmed] |
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