DNA Binding Motif

						

			
Accessions: OLIG3_DBD (HumanTF 1.0), MA0827.1 (JASPAR 2024)

			
Names: OLIG3
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 3, HT-SELEX
Length: 10
Consensus: AmCATATGby
Weblogo: 
PSSM: P0      A      C      G      T
01   1915    204    427    132      A
02    800   1115    208      6      m
03    222   1915      0      3      C
04   1915     10     99     22      A
05      0     26     72   1915      T
06   1915    103     11      0      A
07     56    224      2   1915      T
08      4      4   1915    275      G
09     28    662    904   1010      b
10    265    964    176   1915      y
Type: Heterodimer
Binding TFs: OLIG3_DBD (Helix-loop-helix DNA-binding domain)
Q7RTU3 (Helix-loop-helix DNA-binding domain)
Q7RTU3
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Küspert M, Hammer A, Bösl MR, Wegner M. Olig2 regulates Sox10 expression in oligodendrocyte precursors through an evolutionary conserved distal enhancer. Nucleic Acids Res 39:1280-93 (2011). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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