DNA Binding Motif

						

			
Accessions: AbrB (DBTBS 1.0)

			
Names: AbrB
Organisms: Bacillus subtilis
Libraries: DBTBS 1.0 1
1 Sierro N, Makita Y, de Hoon M, Nakai K. DBTBS: a database of transcriptional regulation in Bacillus subtilis containing upstream intergenic conservation information. Nucleic acids research 36:D93-6 (2008). [Pubmed]
Length: 12
Consensus: vkkTkmCAWwAA
Weblogo: 
PSSM: P0      A      C      G      T
01   0.39   0.31   0.31      0      v
02   0.03      0   0.37   0.59      k
03      0      0   0.37   0.63      k
04   0.04      0   0.21   0.75      T
05   0.04      0   0.51   0.45      k
06   0.34   0.62      0   0.04      m
07      0   0.88   0.09   0.02      C
08      1      0      0      0      A
09   0.68      0      0   0.32      W
10   0.61   0.09      0   0.30      w
11      1      0      0      0      A
12   0.96      0      0   0.04      A
Binding TFs: AbrB (Antidote-toxin recognition MazE)
Binding Sites: abrB_1
aprE_1
citB_1
comK_1
dppA_1
ftsA_1
ftsA_2
hutP_1
kinB_1
pbpE_1
pbpE_2
rbsR_1
rbsR_2
sigH_1
sigW_1
sinI_1
spo0E_1
spoVG_1
yknW_1
yvlA_1
yvqI_1
yxzE_1
			
Publications: Strauch M.A, Spiegelman G.B, Perego M, Johnson W.C, Burbulys D, Hoch J.A. The transition state transcription regulator abrB of Bacillus subtilis is a DNA binding protein. The EMBO journal 8:1615-21 (1989). [Pubmed]


Ferrari E, Howard S.M, Hoch J.A. Effect of stage 0 sporulation mutations on subtilisin expression. Journal of bacteriology 166:173-9 (1986). [Pubmed]


Ogura M, Shimane K, Asai K, Ogasawara N, Tanaka T. Binding of response regulator DegU to the aprE promoter is inhibited by RapG, which is counteracted by extracellular PhrG in Bacillus subtilis. Molecular microbiology 49:1685-97 (2003). [Pubmed]


Kim H.J, Kim S.I, Ratnayake-Lecamwasam M, Tachikawa K, Sonenshein A.L, Strauch M. Complex regulation of the Bacillus subtilis aconitase gene. Journal of bacteriology 185:1672-80 (2003). [Pubmed]


Hamoen L.W, Kausche D, Marahiel M.A, van Sinderen D, Venema G, Serror P. The Bacillus subtilis transition state regulator AbrB binds to the -35 promoter region of comK. FEMS microbiology letters 218:299-304 (2003). [Pubmed]


Hahn J, Kong L, Dubnau D. The regulation of competence transcription factor synthesis constitutes a critical control point in the regulation of competence in Bacillus subtilis. Journal of bacteriology 176:5753-61 (1994). [Pubmed]


Slack F.J, Mueller J.P, Strauch M.A, Mathiopoulos C, Sonenshein A.L. Transcriptional regulation of a Bacillus subtilis dipeptide transport operon. Molecular microbiology 5:1915-25 (1991). [Pubmed]


Strauch M.A. Delineation of AbrB-binding sites on the Bacillus subtilis spo0H, kinB, ftsAZ, and pbpE promoters and use of a derived homology to identify a previously unsuspected binding site in the bsuB1 methylase promote. Journal of bacteriology 177:6999-7002 (1995). [Pubmed]


Fisher S.H, Strauch M.A, Atkinson M.R, Wray L.V. Modulation of Bacillus subtilis catabolite repression by transition state regulatory protein AbrB. Journal of bacteriology 176:1903-12 (1994). [Pubmed]


Strauch M.A. AbrB modulates expression and catabolite repression of a Bacillus subtilis ribose transport operon. Journal of bacteriology 177:6727-31 (1995). [Pubmed]


Qian Q, Lee C.Y, Helmann J.D, Strauch M.A. AbrB is a regulator of the sigma(W) regulon in Bacillus subtilis. FEMS microbiology letters 211:219-23 (2002). [Pubmed]


Strauch M.A. In vitro binding affinity of the Bacillus subtilis AbrB protein to six different DNA target regions. Journal of bacteriology 177:4532-6 (1995). [Pubmed]


Shafikhani S.H, Mandic-Mulec I, Strauch M.A, Smith I, Leighton T. Postexponential regulation of sin operon expression in Bacillus subtilis. Journal of bacteriology 184:564-71 (2002). [Pubmed]


Shafikhani S.H, Leighton T. AbrB and Spo0E control the proper timing of sporulation in Bacillus subtilis. Current microbiology 48:262-9 (2004). [Pubmed]


Zuber P, Losick R. Use of a lacZ fusion to study the role of the spoO genes of Bacillus subtilis in developmental regulation. Cell 35:275-83 (1983). [Pubmed]


Zuber P, Losick R. Role of AbrB in Spo0A- and Spo0B-dependent utilization of a sporulation promoter in Bacillus subtilis. Journal of bacteriology 169:2223-30 (1987). [Pubmed]


Fürbass R, Gocht M, Zuber P, Marahiel M.A. Interaction of AbrB, a transcriptional regulator from Bacillus subtilis with the promoters of the transition state-activated genes tycA and spoVG. Molecular & general genetics : MGG 225:347-54 (1991). [Pubmed]


Hamon M.A, Stanley N.R, Britton R.A, Grossman A.D, Lazazzera B.A. Identification of AbrB-regulated genes involved in biofilm formation by Bacillus subtilis. Molecular microbiology 52:847-60 (2004). [Pubmed]


Jordan S, Rietkötter E, Strauch M.A, Kalamorz F, Butcher B.G, Helmann J.D, Mascher T. LiaRS-dependent gene expression is embedded in transition state regulation in Bacillus subtilis. Microbiology (Reading, England) 153:2530-40 (2007). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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