DNA Binding Motif

Accessions: MYBL2_DBD_4 (HumanTF 1.0), MA0777.1 (JASPAR 2024)
Names: MYBL2
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 3, HT-SELEX
Length: 15
Consensus: rrCCGTTwAACsGyy
Weblogo:
PSSM: P0 A C G T
01 785 34 447 41 r
02 1232 122 722 464 r
03 87 1232 85 39 C
04 107 1232 190 30 C
05 5 0 1232 1 G
06 9 6 24 1232 T
07 0 9 0 1232 T
08 1232 74 77 561 w
09 1232 31 16 4 A
10 1232 38 28 79 A
11 14 1232 6 4 C
12 57 418 467 289 s
13 82 123 1232 95 G
14 228 466 95 766 y
15 40 655 18 577 y
Type: Heterodimer
Binding TFs: P10244 (Myb-like DNA-binding domain, C-myb, C-terminal, Myb-like DNA-binding domain)
MYBL2_DBD (Myb-like DNA-binding domain, Myb-like DNA-binding domain)
P10244
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

Tang H, Goldberg E. A-MYB (MYBL1) stimulates murine testis-specific Ldhc expression via the cAMP-responsive element (CRE) site. Biol Reprod 86:30 (2012). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.