DNA Binding Motif

Accessions: 1zgw_A (3D-footprint 20210203)
Names: Ada polyprotein
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20210203 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: NMR structure of E. Coli Ada protein in complex with DNA
Length: 12
Consensus: tTGCGnntTAAT
Weblogo:
PSSM: P0 A C G T
01 16 8 16 56 t
02 0 0 0 96 T
03 0 0 96 0 G
04 0 96 0 0 C
05 0 0 96 0 G
06 24 24 24 24 n
07 24 24 24 24 n
08 16 16 16 48 t
09 8 8 8 72 T
10 96 0 0 0 A
11 96 0 0 0 A
12 0 0 0 96 T
Binding TFs: 1zgw_A (Metal binding domain of Ada, Bacterial regulatory helix-turn-helix proteins, AraC family, Helix-turn-helix domain)
Binding Sites: 1zgw_B
1zgw_C
Publications: He C, Hus J.C, Sun L.J, Zhou P, Norman D.P, Dötsch V, Wei H, Gross J.D, Lane W.S, Wagner G, Verdine G.L. A methylation-dependent electrostatic switch controls DNA repair and transcriptional activation by E. coli ada. Molecular cell 20:117-29 (2005). [Pubmed]

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