DNA Binding Motif

Accessions: 1oct_C (3D-footprint 20231221)
Names: PROTEIN (OCT-1 POU DOMAIN)
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CRYSTAL STRUCTURE OF THE OCT-1 POU DOMAIN BOUND TO AN OCTAMER SITE: DNA RECOGNITION WITH TETHERED DNA-BINDING MODULES
Length: 8
Consensus: TATGCAAA
Weblogo:
PSSM: P0 A C G T
01 11 8 8 69 T
02 69 8 11 8 A
03 0 9 0 87 T
04 0 0 96 0 G
05 0 96 0 0 C
06 96 0 0 0 A
07 69 11 8 8 A
08 96 0 0 0 A
Binding TFs: 1oct_C (Homeobox domain, Pou domain - N-terminal to homeobox domain)
Binding Sites: 1oct_A
1oct_B
Publications: Klemm J. D., Rould M. A., Aurora R., Herr W., Pabo C. O. Crytsal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules. Cell 77:21-32 (1994). [Pubmed]

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