DNA Binding Motif

Accessions: 1nlw_AB (3D-footprint 20231221)
Names: MAD PROTEIN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of Mad-Max recognizing DNA
Length: 9
Consensus: TGCACGTGC
Weblogo:
PSSM: P0 A C G T
01 7 7 9 73 T
02 7 7 73 9 G
03 0 96 0 0 C
04 96 0 0 0 A
05 7 73 7 9 C
06 0 0 96 0 G
07 0 0 0 96 T
08 0 0 96 0 G
09 7 73 7 9 C
Type: Heterodimer
Binding TFs: 1nlw_A (Helix-loop-helix DNA-binding domain)
1nlw_B (Helix-loop-helix DNA-binding domain)
Binding Sites: 1nlw_F / 1nlw_G
Publications: Nair S.K, Burley S.K. X-ray structures of Myc-Max and Mad-Max recognizing DNA. Molecular bases of regulation by proto-oncogenic transcription factors. Cell 112:193-205 (2003). [Pubmed]

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