DNA Binding Motif

						

			
Accessions: 4uuv_AM (3D-footprint 20231221)

			
Names: ETS TRANSLOCATION VARIANT 4
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of the DNA binding ETS domain of human ETV4 in complex with DNA
Length: 18
Consensus: ACnTCCGnnnnCGGAaGt
Weblogo: 
PSSM: P0      A      C      G      T
01     72      8      8      8      A
02      0     96      0      0      C
03     24     24     24     24      n
04      0      0      0     96      T
05      0     96      0      0      C
06      0     96      0      0      C
07      0      0     96      0      G
08     24     24     24     24      n
09     24     24     24     24      n
10     24     24     24     24      n
11     24     24     24     24      n
12      0     96      0      0      C
13      0      0     96      0      G
14      0      0     96      0      G
15     96      0      0      0      A
16     56     16     16      8      a
17      0      0     96      0      G
18     16     16     16     48      t
Type: Heterodimer
Binding TFs: 4uuv_A (Ets-domain)
4uuv_M (Ets-domain)
Binding Sites: 4uuv_N
4uuv_O
			
Publications: Cooper C.D, Newman J.A, Aitkenhead H, Allerston C.K, Gileadi O. Structures of the Ets Domains of Transcription Factors ETV1, ETV4, ETV5 and FEV: Determinants of DNA Binding and Redox Regulation by Disulfide bond formation. The Journal of biological chemistry : (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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