DNA Binding Motif

						

			
Accessions: ERG_DBD_1 (HumanTF 1.0), MA0474.2 (JASPAR 2024)

			
Names: ERG
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 2, HT-SELEX
Length: 10
Consensus: ACCGGAArTg
Weblogo: 
PSSM: P0      A      C      G      T
01   4566    268    848    928      A
02    646   4566    398     97      C
03    635   4566     22      6      C
04      1      0   4566      0      G
05      0      1   4566     29      G
06   4566     20      0      7      A
07   4566    119      7   1245      A
08   1990    100   2576     28      r
09    137   1586    355   4566      T
10   1006   1100   1668    792      g
Type: Heterodimer
Binding TFs: P11308 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
ERG_DBD (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
P11308 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
P11308
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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