DNA Binding Motif

Accessions: 1u8r_ABCD (3D-footprint 20231221)
Names: Iron-dependent repressor ideR
Organisms: Mycobacterium tuberculosis, strain ATCC 25618 / H37Rv
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of an IdeR-DNA Complex Reveals a Conformational Change in Activated IdeR for Base-specific Interactions
Length: 17
Consensus: AGCAcAGGCTgCCCTAA
Weblogo:
PSSM: P0 A C G T
01 96 0 0 0 A
02 7 7 74 8 G
03 7 75 7 7 C
04 96 0 0 0 A
05 9 65 11 11 c
06 96 0 0 0 A
07 0 0 96 0 G
08 0 0 96 0 G
09 0 96 0 0 C
10 0 0 0 96 T
11 14 11 60 11 g
12 0 96 0 0 C
13 0 96 0 0 C
14 7 74 8 7 C
15 0 0 0 96 T
16 81 4 4 7 A
17 88 2 2 4 A
Binding TFs: 1u8r_A / 1u8r_B / 1u8r_C / 1u8r_D (Iron dependent repressor, N-terminal DNA binding domain, Iron dependent repressor, metal binding and dimerisation domain, FeoA domain, Winged helix DNA-binding domain)
Binding Sites: 1u8r_E
1u8r_F
Publications: Wisedchaisri G, Holmes R.K, Hol W.G. Crystal structure of an IdeR-DNA complex reveals a conformational change in activated IdeR for base-specific interactions. Journal of molecular biology 342:1155-69 (2004). [Pubmed]

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