DNA Binding Motif
| Accessions: | 5i50_B (3D-footprint 20231221) |
| Names: | Myc proto-oncogene protein |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Description: | Structure of OmoMYC bound to double-stranded DNA |
| Length: | 5 |
| Consensus: | CgTGG |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 11 67 9 9 C 02 18 18 42 18 g 03 2 4 2 88 T 04 0 0 96 0 G 05 4 4 84 4 G |
| Binding TFs: | 5i50_B (Helix-loop-helix DNA-binding domain, Myc leucine zipper domain) |
| Binding Sites: | 5i50_C 5i50_D |
| Publications: | Jung LA, Gebhardt A, Koelmel W, Ade CP, Walz S, Kuper J, von Eyss B, Letschert S, Redel C, d'Artista L, Biankin A, Zender L, Sauer M, Wolf E, Evan G, Kisker C, Eilers M. OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors. Oncogene : (2016). [Pubmed] |
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