DNA Binding Motif
| Accessions: | PyrR (DBTBS 1.0) |
| Names: | PyrR |
| Organisms: | Bacillus subtilis |
| Libraries: | DBTBS 1.0 1 1 Sierro N, Makita Y, de Hoon M, Nakai K. DBTBS: a database of transcriptional regulation in Bacillus subtilis containing upstream intergenic conservation information. Nucleic acids research 36:D93-6 (2008). [Pubmed] |
| Length: | 20 |
| Consensus: | ArTCCAGAGAGGyTkvrAAG |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 3 0 0 0 A 02 1 0 2 0 r 03 0 0 0 3 T 04 0 3 0 0 C 05 0 3 0 0 C 06 3 0 0 0 A 07 0 0 3 0 G 08 3 0 0 0 A 09 0 0 3 0 G 10 3 0 0 0 A 11 0 0 3 0 G 12 0 0 3 0 G 13 0 2 0 1 y 14 0 0 0 3 T 15 0 0 2 1 k 16 1 1 1 0 v 17 1 0 2 0 r 18 3 0 0 0 A 19 3 0 0 0 A 20 0 0 3 0 G |
| Binding TFs: | PyrR (Phosphoribosyl transferase domain) |
| Binding Sites: | pyrB pyrP pyrR_2 |
| Publications: | Lu Y, Turner R.J, Switzer R.L. Function of RNA secondary structures in transcriptional attenuation of the Bacillus subtilis pyr operon. Proceedings of the National Academy of Sciences of the United States of America 93:14462-7 (1996). [Pubmed] Quinn C.L, Stephenson B.T, Switzer R.L. Functional organization and nucleotide sequence of the Bacillus subtilis pyrimidine biosynthetic operon. The Journal of biological chemistry 266:9113-27 (1991). [Pubmed] Turner R.J, Lu Y, Switzer R.L. Regulation of the Bacillus subtilis pyrimidine biosynthetic (pyr) gene cluster by an autogenous transcriptional attenuation mechanism. Journal of bacteriology 176:3708-22 (1994). [Pubmed] Ghim S.Y, Switzer R.L. Characterization of cis-acting mutations in the first attenuator region of the Bacillus subtilis pyr operon that are defective in pyrimidine-mediated regulation of expression. Journal of bacteriology 178:2351-5 (1996). [Pubmed] Lu Y, Switzer R.L. Evidence that the Bacillus subtilis pyrimidine regulatory protein PyrR acts by binding to pyr mRNA at three sites in vivo. Journal of bacteriology 178:5806-9 (1996). [Pubmed] Lu Y, Switzer R.L. Transcriptional attenuation of the Bacillus subtilis pyr operon by the PyrR regulatory protein and uridine nucleotides in vitro. Journal of bacteriology 178:7206-11 (1996). [Pubmed] Bonner E.R, D'Elia J.N, Billips B.K, Switzer R.L. Molecular recognition of pyr mRNA by the Bacillus subtilis attenuation regulatory protein PyrR. Nucleic acids research 29:4851-65 (2001). [Pubmed] Zhang H, Switzer R.L. Transcriptional pausing in the Bacillus subtilis pyr operon in vitro: a role in transcriptional attenuation?. Journal of bacteriology 185:4764-71 (2003). [Pubmed] Turner R.J, Bonner E.R, Grabner G.K, Switzer R.L. Purification and characterization of Bacillus subtilis PyrR, a bifunctional pyr mRNA-binding attenuation protein/uracil phosphoribosyltransferase. The Journal of biological chemistry 273:5932-8 (1998). [Pubmed] Zhang H, Jørgensen C.M, Switzer R.L. Mutations affecting transcription pausing in the Bacillus subtilis pyr operon. Archives of microbiology 184:101-7 (2005). [Pubmed] Lu Y, Turner R.J, Switzer R.L. Roles of the three transcriptional attenuators of the Bacillus subtilis pyrimidine biosynthetic operon in the regulation of its expression. Journal of bacteriology 177:1315-25 (1995). [Pubmed] |
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