DNA Binding Motif

Accessions: 4tnt_AB (3D-footprint 20231221)
Names: Mineralocorticoid receptor
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of the human mineralocorticoid receptor in complex with DNA
Length: 13
Consensus: GnaCannnTGnnC
Weblogo:
PSSM: P0 A C G T
01 10 1 85 0 G
02 24 24 24 24 n
03 64 12 10 10 a
04 0 96 0 0 C
05 64 10 12 10 a
06 24 24 24 24 n
07 24 24 24 24 n
08 24 24 24 24 n
09 0 10 0 86 T
10 0 0 96 0 G
11 24 24 24 24 n
12 24 24 24 24 n
13 0 96 0 0 C
Binding TFs: 4tnt_A / 4tnt_B (Zinc finger, C4 type (two domains))
Binding Sites: 4tnt_D
4tnt_C
Publications: Hudson W.H, Youn C, Ortlund E.A. Crystal structure of the mineralocorticoid receptor DNA binding domain in complex with DNA. PloS one 9:e107000 (2014). [Pubmed]

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